The effects of repetitive electric cardiac stimulation in dogs with normal hearts, complete heart block and experimental cardiac arrest.

نویسندگان

  • T E STARZL
  • R A GAERTNER
  • R C WEBB
چکیده

Direct cardiac stimulation mas conducted in the open chest. In normal animals, auricular stimulation a t frequencies faster than the spontaneous rate caused little change in vascular pressures or cardiac output. Comparable ventricular stimulation in the same animals caused falls in cardiac output and blood pressure, with elevations in venous pressure. In contrast, ventricular stimulation in animals with complete heart block caused elevations in cardiac output and blood pressure, and declines in venous pressure. A study was also made of repetitive stimulation in experimental cardiac arrest. Occasionally pacemaking was of value in the resuscitation, but in most cases effective contractions could not be induced with stimulation.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Effects of Repetitive Electric Cardiac Stimulation

Direct cardiac stimulation was conducted in the open chest. In normal animals, auricular stimulation at frequencies faster than the spontaneous rate caused little change in vascular pressures or cardiac output. Comparable ventricular stimulation in the same animals caused falls in cardiac output and blood pressure, with elevations in venous pressure. In contrast, ventricular stimulation in anim...

متن کامل

Long-term subthreshold electrical stimulation of the left stellate ganglion and a canine model of sudden cardiac death.

OBJECTIVES We sought to develop a high-yield canine model of sudden cardiac death (SCD). BACKGROUND Because electrical stimulation is a powerful means to elicit nerve sprouting, we hypothesize that subthreshold electrical stimulation is more effective than nerve growth factor (NGF) infusion in inducing nerve sprouting and SCD in dogs with myocardial infarction (MI) and complete atrioventricul...

متن کامل

A Comparison Between the Effects of Xylazine-Ketamine and Xylazine-Thiopental Combinations on Cardiac Rhythm in Dogs

Objective- To compare the effects of xylazine-ketamine and xylazine-thiopental on cardiac rhythm indogs.Design- Experimental study.Animals- 15 mixed-bred, adult dogs of either sex.Procedures- Following premedication with xylazine HCI, either ketarnine HCI or sodium thiopentalwere administered to dogs. Cardiac rhythm was evaluated before as well as 15,30,45, and 60 minutes and3 days after induct...

متن کامل

Role of Fructose as a Potent Antiarrhythmic and Anti-infarct agent in Isolated Rat Heart

In the current study, effects of acute short term administration of fructose on cardiac arrhythmias and myocardial infarction size following ischemia/reperfusion were investigated in isolated rat heart. The hearts were subjected to 30 min zero flow global ischemia followed by 120 min reperfusion. In the control group, the hearts were perfused by normal drug free Krebs-Henseleit (K/H) solution t...

متن کامل

Role of Fructose as a Potent Antiarrhythmic and Anti-infarct agent in Isolated Rat Heart

In the current study, effects of acute short term administration of fructose on cardiac arrhythmias and myocardial infarction size following ischemia/reperfusion were investigated in isolated rat heart. The hearts were subjected to 30 min zero flow global ischemia followed by 120 min reperfusion. In the control group, the hearts were perfused by normal drug free Krebs-Henseleit (K/H) solution t...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Circulation

دوره 11 6  شماره 

صفحات  -

تاریخ انتشار 1955